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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAH
All Species:
32.12
Human Site:
Y401
Identified Species:
64.24
UniProt:
P16930
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P16930
NP_000128.1
419
46374
Y401
G
Y
C
Q
G
D
G
Y
R
I
G
F
G
Q
C
Chimpanzee
Pan troglodytes
XP_001155476
421
46561
Y403
G
Y
C
Q
G
D
G
Y
R
I
G
F
G
Q
C
Rhesus Macaque
Macaca mulatta
XP_001109382
419
46350
Y401
G
Y
C
Q
G
D
G
Y
R
I
G
F
G
Q
C
Dog
Lupus familis
XP_852646
406
45079
T388
G
F
T
F
G
Q
G
T
C
W
L
L
E
P
F
Cat
Felis silvestris
Mouse
Mus musculus
P35505
419
46085
Y401
G
H
C
Q
G
D
G
Y
R
V
G
F
G
Q
C
Rat
Rattus norvegicus
P25093
419
45957
Y401
G
H
C
Q
G
D
G
Y
R
V
G
F
G
Q
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_413855
419
46530
Y401
G
Y
C
Q
G
S
G
Y
R
V
G
F
G
Q
C
Frog
Xenopus laevis
NP_001080458
420
46648
Y401
G
Y
C
Q
G
E
G
Y
R
V
G
F
G
T
C
Zebra Danio
Brachydanio rerio
NP_955895
348
38736
G334
E
G
Q
G
F
R
V
G
F
G
L
C
E
G
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524830
417
46453
L398
G
H
C
E
K
N
G
L
R
I
G
F
G
E
C
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_509083
418
46026
R403
V
C
E
K
N
G
V
R
I
G
F
G
E
C
R
Sea Urchin
Strong. purpuratus
XP_787535
389
42602
Y373
G
H
C
Q
G
E
G
Y
R
V
G
F
G
E
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
96.9
75.8
N.A.
89
88.5
N.A.
N.A.
80.1
74.5
62.5
N.A.
60.3
N.A.
64.4
63
Protein Similarity:
100
99
98
79.7
N.A.
95.2
94.2
N.A.
N.A.
89.2
83.8
72.3
N.A.
73.7
N.A.
76.8
75.1
P-Site Identity:
100
100
100
20
N.A.
86.6
86.6
N.A.
N.A.
86.6
80
0
N.A.
60
N.A.
0
66.6
P-Site Similarity:
100
100
100
26.6
N.A.
100
100
N.A.
N.A.
93.3
93.3
0
N.A.
86.6
N.A.
6.6
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
9
75
0
0
0
0
0
9
0
0
9
0
9
67
% C
% Asp:
0
0
0
0
0
42
0
0
0
0
0
0
0
0
0
% D
% Glu:
9
0
9
9
0
17
0
0
0
0
0
0
25
17
0
% E
% Phe:
0
9
0
9
9
0
0
0
9
0
9
75
0
0
9
% F
% Gly:
84
9
0
9
75
9
84
9
0
17
75
9
75
9
0
% G
% His:
0
34
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
9
34
0
0
0
0
0
% I
% Lys:
0
0
0
9
9
0
0
0
0
0
0
0
0
0
9
% K
% Leu:
0
0
0
0
0
0
0
9
0
0
17
9
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
9
9
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% P
% Gln:
0
0
9
67
0
9
0
0
0
0
0
0
0
50
0
% Q
% Arg:
0
0
0
0
0
9
0
9
75
0
0
0
0
0
9
% R
% Ser:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
9
% S
% Thr:
0
0
9
0
0
0
0
9
0
0
0
0
0
9
0
% T
% Val:
9
0
0
0
0
0
17
0
0
42
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% W
% Tyr:
0
42
0
0
0
0
0
67
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _